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KMID : 1001920120520010055
Journal of Korean Neurosurgical Society
2012 Volume.52 No. 1 p.55 ~ p.57
Alveolar Soft Part Sarcoma Metastasized to Both the Skull and the Brain
Shin Tae-Hee

Jung Young-Jin
Kim Oh-Lyong
Kim Min-Su
Abstract
Alveolar soft part sarcoma (ASPS) with skull and brain metastases is extremely rare. A 53-year-old patient diagnosed as skull metastasis of ASPS visited our clinic complaining of an outgrowing scalp mass in spite of radiation therapy. Past medical history revealed that the patient had been diagnosed and treated for ASPS of the thigh 4 years ago. Magnetic resonance imaging revealed a hyperintense ovoid mass on the T2-weighted image, an isointense on the T1-weighted image, and a homogeneous enhanced mass with gadolinium. Another small-sized enhanced mass with mild peritumoral swelling was found at the deep white matter of the left frontal lobe. A gross total resection of the skull lesion with cranioplasty was performed for the surgical defect. A histologic examination of the specimens revealed metastatic ASPS involving the skull. Surgery with a total removal of the lesions may be effective for improving a patient¡¯s symptoms especially from neurological dysfunction.
KEYWORD
Alveolar soft part sarcoma, Brain metastasis, Sarcoma, Surgery
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